CHEMICAL

Structural elucidation studies of organic compounds

• High field NMR
• MS3 mass spectrometry
• FTIR spectroscopy
• Polarimetry
• UV spectrophotometry

Synthesis

• Analysis of chiral molecules
• Separation of enantiomers
• Determination of enantiomer excess
• Ester selective synthesis
• Purification of enantiomers

Intermediary and raw material control according to European Pharmacopeia or client’s requirements

• Residual solvents
• Impurities
• Related substances
• Assay
• Identification
• Viscosity
• Water content
• Heavy metals
• Microbiological control
• Any other specified by the product’s requirements

Isolation, purification and identification of products and impurities

• Transfer of analytical scale methods to semi preparative scale
• Scaffolds, synthesis intermediaries and final products purification
• Structural elucidation

Analytical methods

• Design and set up of methods for physicochemical and microbiological analysis
• Method validation according to ICH

Surface and environmental control in production rooms