InKemia IUCT group has the following capacities in the Chemicals synthesis sector:

Medicinal chemistry

  • Design and synthesis of new chemical entities (Hit-finding)
  • Design and synthesis to obtain libraries by parallel synthesis
  • Hit to lead and lead optimization
  • Optimization of synthetic routes and scale up

Custom Synthesis

  • Synthesis of building blocks and non commercial scaffolds
  • Synthesis of patterns and impurities
  • Synthesis of reference compounds and metabolites

New Synthetic Routes

  • Set up of new synthetic routes
  • Design of new synthetic routes that are not published or patented
  • Experimental design and optimization of chemical synthesis: yields, selectivity, crystallization and impurities.
  • Minimization of synthesis steps and isolations
  • Design and synthesis of new compounds
  • Generation reduction of toxic and dangerous by-products
  • Processes without salt generation
  • Processes without solvents
  • Development of processes with minimum solvent consumption
  • Optimization of the synthesis methodology in both solid and liquid phase
  • Safer reactive compounds

Optimization of chemical processes

  • Optimization of processes using LABMAX (kilolab) automatic reactor
  • Cost reduction by redesigning of synthetic processes
  • Substitution of dangerous reactive compounds
  • Development of validation processes and scale up


Revaluation of industry’s by-products

  • Use of by-products as raw material for new processes
  • New applications for industrial by-products


Structural Elucidation Studies

  • Structural elucidation studies 

Chemical biotransformation

  • Chemical synthesis using microorganisms
  • Fermentation processes
  • Biotechnological processes for chemical products of large tonnage (biopolymers, solvents, bio monomers) and fine chemistry
  • Obtention of novelty enzymes as industrial biocatalysts for fine chemistry and large productions
  • Development of minimal and artificial microorganisms: synthetic biology

Alternative Solvents

  • Solvent substitution
  • Development of new solvents with low toxicological profile for industrial use
  • Synthesis of active principals with safe solvents
  • New uses for alternative solvents


Instrumental Techniques


  • LABMAX (kilolab) automatic reactor
    • Reactor with computerized control of the reaction variables: temperature of the reaction, temperature of the jacket, agitation speed, flow of the reactive addition, pH control, control probes, distillation control.
    • Reactor from 1-3 L, also pressure reaction up to 1 litre.


  • Gas Chromatography- Flame Ionization Detector (GC-FID)
  • Gas Chromatography Mass Spectrometry (GC-MS)
  • Gas Chromatography, Head Space
  • HPLC, Mass Spectrometry (MS)
  • Flame Atomic absorption spectroscopy
  • Graphite furnace atomic absorption spectrometry
  • FT-IR
  • molecular absorption spectroscopy, UV-Visible
  • NMR (400 MHz)



  •  +34 93 579 34 32
  •  +34 93 570 57 45
  •  C\ Àlvarez de Castro, 63, 08100
    Mollet del Vallès (Barcelona)